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drug substance - メーカー・企業6社の製品一覧とランキング

更新日: 集計期間:Aug 06, 2025~Sep 02, 2025
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drug substanceのメーカー・企業ランキング

更新日: 集計期間:Aug 06, 2025~Sep 02, 2025
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  1. 相互薬工 Tokyo//Chemical
  2. 立山化成 Toyama//Manufacturing and processing contract
  3. ビオブリッジ Tokyo//others 本社
  4. ファーマテック Tokyo//Pharmaceuticals and Biotechnology
  5. 5 Cytiva Tokyo//others

drug substanceの製品ランキング

更新日: 集計期間:Aug 06, 2025~Sep 02, 2025
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  1. Sogo Pharmaceutical Co., Ltd. Company Profile 相互薬工
  2. Tateyama Kasei Co., Ltd. Kyushu Factory 立山化成
  3. BioBridge Corporation Business Introduction ビオブリッジ 本社
  4. Freeze & Go Solutions Cytiva
  5. 4 [Column] Management Strategies for Starting Materials in Active Pharmaceutical Ingredients スペラファーマ

drug substanceの製品一覧

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Tateyama Kasei Co., Ltd. Kyushu Factory

Five manufacturing buildings, a quality control building, an office building, and a wastewater treatment facility are all included! It has a manufacturing license for pharmaceuticals.

Tateyama Kasei Co., Ltd.'s Kyushu factory is located in Tagawa City, which is situated in the central part of Fukuoka Prefecture. It began operations in 1972 and is equipped with five manufacturing buildings, a quality control building, an office building, and wastewater treatment facilities. Notable equipment includes an indirect cooling type ultra-low temperature reaction device and a filtration dryer. The factory holds a manufacturing license for pharmaceuticals and has two lines of 6000L active pharmaceutical ingredient purification equipment, making it suitable for the production of relatively large quantities of stable active pharmaceutical ingredients. [Features] - Possesses an indirect cooling type ultra-low temperature reaction device and a filtration dryer - Holds a manufacturing license for pharmaceuticals - Well-suited for the production of relatively large quantities of stable active pharmaceutical ingredients *For more details, please refer to the PDF document or feel free to contact us.

  • Contract manufacturing
  • Chemicals

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Freeze & Go Solutions

Are you particular about the "freezing method" of pharmaceutical raw materials? It is possible to freeze and thaw raw materials more safely and securely while maintaining quality!

Of the biopharmaceutical active ingredients, 59.4% are transported in a frozen state. Therefore, the development of controllable and efficient freezing and thawing technologies is increasingly in demand. For example, in the development of COVID-19 vaccines, there has been a growing emphasis on storage and transportation methods, highlighting the necessity for these solutions. Recently, the combination of Allegro BioContainers and RoSS Technology has resulted in the development of an excellent active ingredient management solution through synergistic effects. It allows for the control of frozen active ingredients between the purification process and the formulation and filling processes, enabling stable and safe storage and transportation. Additionally, it prevents losses of active ingredients due to the breakage of frozen single-use packs, bringing the risk of loss close to 0%.

  • others

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Sogo Pharmaceutical Co., Ltd. Company Profile

We will leverage our forward-thinking creativity and technological capabilities to contribute to the future of life sciences.

Sogo Yakuco started as an active pharmaceutical ingredient manufacturer producing substances such as Sulfisozine, Sulfadimethoxine, and Taurine. Leveraging the synthetic technologies acquired through active pharmaceutical ingredients, we engage in the development and manufacturing of functional cosmetic ingredients, recording materials, and electronic materials. With the keywords "safety," "technical capability," "speed," "quality," and "environment," we strive to meet the needs of the life sciences sector with a spirit of "challenge" and continuous corporate efforts. 【Business Activities】 ■ Manufacturing, sales, and import/export of pharmaceutical active ingredients, veterinary pharmaceuticals, and functional cosmetic ingredients ■ Manufacturing, sales, and import/export of fine chemical products such as specialty chemicals and chemical industrial products *For more details, please refer to the PDF materials or feel free to contact us.

  • Chemicals

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[Column] Management Strategies for Starting Materials in Active Pharmaceutical Ingredients

The selection of starting materials significantly impacts the manufacturing cost of active pharmaceutical ingredients. We would like to introduce our management strategy for starting materials in active pharmaceutical ingredient production.

The selection of starting materials (hereinafter referred to as starting materials) for applications is proposed by pharmaceutical companies in accordance with the general principles of ICH guideline Q11, but it is often the case that they receive frequent inquiries from authorities before approval. At SpiraPharma, when selecting starting materials, organic chemists and analytical chemists collaborate to propose which compounds are suitable as starting materials based on the manufacturing process. Additionally, when establishing management strategies for starting materials, we can obtain data to support responses to authorities through investigations of the behavior of key related substances. For our customers who are challenging the creation of new pharmaceuticals, we will continue to leverage our cultivated technology and experience while furthering our expertise. *For more detailed information on the column, please refer to the related link. For further inquiries, please feel free to contact us.

  • Other contract manufacturing

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Seminar on the Pharmaceutical Active Ingredient Manufacturing Process Utilizing Catalytic Asymmetric Synthesis

[December 15 Event] A must-see for those involved in the synthesis of low molecular weight pharmaceuticals! Introduction to efforts in asymmetric synthesis reactions and more.

We are pleased to announce that our company will be hosting a webinar on "Pharmaceutical Active Ingredient Manufacturing Processes Utilizing Catalytic Asymmetric Synthesis" on December 15th (Thursday). In the synthesis of active pharmaceutical ingredients for low molecular weight drugs, when the target compound is a chiral compound with an asymmetric center, utilizing asymmetric synthesis that can synthesize the desired stereoisomer with high selectivity is extremely useful in the industry. At SpiraPharma, we have received requests from various customers to examine the asymmetric synthesis of target compounds, and we are advancing the application of asymmetric reactions centered on catalytic asymmetric hydrogenation to pharmaceutical processes. In this webinar, we will introduce our efforts in asymmetric synthesis reactions. We encourage anyone interested to participate. 【Event Overview】 ■ Date and Time: December 15th (Thursday) 11:00 AM - 11:30 AM ■ Participation: Free ■ Venue: Webinar via Teams *For more details, please refer to the related links or feel free to contact us.

  • Pharmaceutical materials and carriers

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Tateyama Chemical Co., Ltd. Quality Assurance System

With "creative practice" as a keyword, we are constantly reevaluating our quality assurance system.

Our company started with the production of methyl ephedrine, an active pharmaceutical ingredient (API) for expectorants. The manufacturing of APIs and their quality control are the very roots of Tateyama Chemical. Aiming for world-class quality assurance, we achieve global-level quality assurance that complies not only with Japan's GMP, which is the standard for pharmaceutical manufacturing and quality control, but also with PIC/S GMP, to supply safe, effective, and high-quality pharmaceuticals to countries around the world. To respond to the trust of various customers and ultimately the end users, we will continuously update our quality control system. 【Management Policy】 ■ Development of new products ■ Refinement of technology ■ Thorough implementation of 5S and quality control ■ Raising awareness of environmental conservation and health and safety *For more details, please refer to the PDF materials or feel free to contact us.

  • Contract manufacturing
  • Chemicals

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Pharmatech Co., Ltd. "Company Profile"

Contract manufacturing of raw materials and intermediates is handled by Pharmatech Co., Ltd.

Pharmatech Co., Ltd. is a company located in Chuo Ward, Tokyo, engaged in the sales of pharmaceutical raw materials and intermediates. With a customer-oriented approach as our foundation, we aim to provide high-quality materials and services not only in Japan but also around the world. We consider it our significant mission to contribute to society through the sale of various raw materials related to pharmaceuticals, pharmaceutical intermediates, health foods, cosmetics, biochemical products, clinical testing reagents, industrial chemicals, and more. 【Business Activities】 ■ Export and sales of pharmaceutical raw materials ■ Sales of pharmaceutical intermediates, chemical products, toxic substances, reagents, and clinical testing reagents ■ Wholesale sales of pharmaceutical raw materials ■ Import and export, and domestic sales of food, food additives, and health foods ■ Sales of traditional Chinese medicine and plant extracts *For more details, please refer to our catalog. Feel free to contact us with any inquiries.

  • Chemicals

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BioBridge Corporation Business Introduction

Due to our long-standing track record, we have been entrusted with numerous agency operations.

BioBridge Co., Ltd. has been expanding its transactions with high-quality pharmaceutical raw material manufacturers and contract laboratories, primarily in Europe and including Asia, since its establishment. We are also engaged in transactions with domestic pharmaceutical and chemical companies. We handle a wide range of products, from antibiotic raw material intermediates to generic active pharmaceutical ingredients, and radioactive isotopes (14C, 3H). 【Business Activities】 ■ Sales of pharmaceutical raw materials, radioactive isotopes, and chemicals ■ Liaison office and agency services for overseas pharmaceutical companies, testing and inspection organizations, and contract manufacturing companies ■ Application services for registration of pharmaceutical raw materials, among others *For more details, please download the PDF or feel free to contact us.

  • Pharmaceutical Intermediates

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Pharmaceutical Active Ingredient Division (Pharmaceutical Research Headquarters) Business and Technology

Process optimization is possible! We propose a balanced active pharmaceutical ingredient development plan that considers speed, cost-effectiveness, and quality.

We would like to introduce our pharmaceutical active ingredient division (Pharmaceutical Research Headquarters) and its business and technology. We flexibly utilize a network of reliable partner contract manufacturers to build and propose an optimal active ingredient manufacturing supply chain tailored to specific purposes. With world-class pharmaceutical development technology and assured quality, we provide "the development of active ingredient manufacturing methods from 'zero' that meet global application requirements" and "a seamless and consistent active ingredient manufacturing process and quality design from preclinical stages to obtaining marketing approval." 【Features】 ■ Development of active ingredient manufacturing methods from 'zero' based on technology and know-how cultivated over many years at major domestic pharmaceutical companies. ■ Establishment of active ingredient manufacturing methods and quality design according to development stages and applications. ■ Flexible response to active ingredient manufacturing requests. ■ Accurate support for application processes (clinical trials and commercial use). *For more details, please refer to the PDF materials or feel free to contact us.

  • Other contract services
  • Technology Development

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[Technology and Achievements Introduction] Absorption Improvement Technology (Nanosized Formulation)

Introducing the correlation diagram of particle size and surface area! It is applied to investigational drugs targeting compounds in the development stage.

We would like to introduce Spela Pharma's "Absorption Improvement Technology." By using nano-sized active pharmaceutical ingredients, we enhance bioavailability. We have successfully developed formulations using this technology and are applying it to investigational drugs targeting compounds in the development stage. On our website, we provide a correlation chart of particle size and surface area, as well as graphs showing plasma concentration in dogs for nano-particles and jet-milled active pharmaceutical ingredients, so please check the related links below. [Features] ■ Improved bioavailability through nano-sized active pharmaceutical ingredients ■ Successful development of formulations using this technology ■ Application to investigational drugs targeting compounds in the development stage *For more details, please refer to the PDF materials or feel free to contact us.

  • Other contract services
  • Technology Development

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[Thank You] CPhI Japan 2022

Thank you for attending CPhI Japan 2022 (International Pharmaceutical Development Exhibition)!

Sperafarma exhibited at CPhI Japan 2022 (International Pharmaceutical Development Exhibition, April 20-22, Tokyo Big Sight) and welcomed many customers to our booth. As a CDMO capable of providing a wide range of services from early-stage R&D to the manufacturing of clinical trial drugs, commercial manufacturing, and raw material procurement, we will accelerate our support for pharmaceutical development. We would like to express our gratitude to everyone who provided us with opportunities for exchanging opinions and sharing information. 【Overview of Presentations at the Booth】 ■ Screening technologies required in active pharmaceutical ingredient research - catalyst selection, crystallization - ■ Mutagenic impurities in pharmaceuticals (active pharmaceutical ingredients) - development of testing methods and analysis examples - *For more details, please refer to the PDF materials or feel free to contact us.

  • Fine chemicals (compounds, derivatives, catalysts, etc.)
  • Other Testing Contract
  • Other analytical and testing equipment

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[CPhI Seminar Report] Mutagenic Impurities in Pharmaceuticals (Active Pharmaceutical Ingredients)

Development of testing methods and analysis examples! Established over 300 analytical methods that can guarantee PMI residues below 10 ppm!

At "CPhI Japan 2022," we held a presentation in our booth regarding ICH M7 compliance from the Development and Analytical Research Headquarters. We introduced the day's content, including "About ICH M7," "For the Development of Trace Analysis Methods," and "Examples of Method Validation." Please take a moment to read it. [Contents] ■ About ICH M7 ■ For the Development of Trace Analysis Methods ■ Examples of Method Validation ■ Conclusion *For more details, please refer to the related links page or feel free to contact us.

  • Other Testing Contract

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